Additive impact of HER2‐/PTK6‐RNAi on interactions with HER3 or IGF‐1R leads to reduced breast cancer progression in vivo

The human epidermal growth factor receptor 2 (HER2) and the protein tyrosine kinase 6 (PTK6) are often co‐ and over‐expressed in invasive breast cancers. At early diagnosis, only distinct groups, such as HER2‐or hormone receptor‐positive benefit from a targeted therapy. However, a part of these tumo...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Falkenberg, Natalie, Anastasov, Nataša, Höfig, Ines, Bashkueva, Ksenia, Lindner, Katrin, Höfler, Heinz, Rosemann, Michael, Aubele, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528674/
https://ncbi.nlm.nih.gov/pubmed/25241146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.08.012
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