Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells

BACKGROUND: There is evidence that the extent of the G2/M arrest following irradiation is correlated with tumour cell survival and hence therapeutic success. We studied the regulation of cellular response to radiation treatment by miR-21-mediated modulation of cell cycle progression in breast cancer...

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Bibliographic Details
Main Authors: Anastasov, Nataša, Höfig, Ines, Vasconcellos, Iria Gonzalez, Rappl, Kristina, Braselmann, Herbert, Ludyga, Natalie, Auer, Gert, Aubele, Michaela, Atkinson, Michael J
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573984/
https://ncbi.nlm.nih.gov/pubmed/23216894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-7-206
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