Osteoblast‐derived sphingosine 1‐phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis‐derived prostate cancer cells

Sphingosine 1‐phosphate (S1P) plays important roles in cell proliferation, differentiation or survival mainly through its surface G‐protein‐coupled receptors S1P1−5. Bone represents the major site of metastasis for prostate cancer (CaP) cells, which rely on bone‐derived factors to support their prol...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Brizuela, Leyre, Martin, Claire, Jeannot, Pauline, Ader, Isabelle, Gstalder, Cécile, Andrieu, Guillaume, Bocquet, Magalie, Laffosse, Jean-Michel, Gomez-Brouchet, Anne, Malavaud, Bernard, Sabbadini, Roger A., Cuvillier, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528572/
https://ncbi.nlm.nih.gov/pubmed/24768038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.04.001
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