Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse

Patient derived xenografts (PDXs) are increasingly appreciated models in cancer research, particularly for preclinical testing, as they reflect the patient's tumor biology more accurately than cancer cell lines. We have established a collection of 20 breast PDXs and characterized their biologic...

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Vydáno v:Mol Oncol
Hlavní autoři: du Manoir, Stanislas, Orsetti, Béatrice, Bras-Gonçalves, Rui, Nguyen, Tien-Tuan, Lasorsa, Laurence, Boissière, Florence, Massemin, Blandine, Colombo, Pierre-Emmanuel, Bibeau, Frédéric, Jacot, William, Theillet, Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2013
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528550/
https://ncbi.nlm.nih.gov/pubmed/24394560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.11.010
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