Ovarian carcinoma patient derived xenografts reproduce their tumor of origin and preserve an oligoclonal structure

Advanced Epithelial Ovarian Cancer (EOC) patients frequently relapse by 24 months and develop resistant disease. Research on EOC therapies relies on cancer cell lines established decades ago making Patient Derived Xenografts (PDX) attractive models, because they are faithful representations of the o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Colombo, Pierre-Emmanuel, du Manoir, Stanislas, Orsetti, Béatrice, Bras-Gonçalves, Rui, Lambros, Mario B., MacKay, Alan, Nguyen, Tien-Tuan, Boissiére, Florence, Pourquier, Didier, Bibeau, Frédéric, Reis-Filho, Jorge S., Theillet, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695063/
https://ncbi.nlm.nih.gov/pubmed/26334103
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