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Establishment of a human 3D lung cancer model based on a biological tissue matrix combined with a Boolean in silico model

For the development of new treatment strategies against cancer, understanding signaling networks and their changes upon drug response is a promising approach to identify new drug targets and biomarker profiles. Pre‐requisites are tumor models with multiple read‐out options that accurately reflect th...

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Detalles Bibliográficos
Publicado en:Mol Oncol
Main Authors: Stratmann, Anna T., Fecher, David, Wangorsch, Gaby, Göttlich, Claudia, Walles, Thorsten, Walles, Heike, Dandekar, Thomas, Dandekar, Gudrun, Nietzer, Sarah L.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528544/
https://ncbi.nlm.nih.gov/pubmed/24388494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.11.009
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