A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds

In the present study, we combined an in vitro 3D lung tumor model with an in silico model to optimize predictions of drug response based on a specific mutational background. The model is generated on a decellularized porcine scaffold that reproduces tissue-specific characteristics regarding extracel...

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Detaylı Bibliyografya
Yayımlandı:J Vis Exp
Asıl Yazarlar: Göttlich, Claudia, Müller, Lena C., Kunz, Meik, Schmitt, Franziska, Walles, Heike, Walles, Thorsten, Dandekar, Thomas, Dandekar, Gudrun, Nietzer, Sarah L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MyJove Corporation 2016
Konular:
Bioengineering
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841364/
https://ncbi.nlm.nih.gov/pubmed/27077967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53885
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