Standardized decision support in next generation sequencing reports of somatic cancer variants

Of hundreds to thousands of somatic mutations that exist in each cancer genome, a large number are unique and non‐recurrent variants. Prioritizing genetic variants identified via next generation sequencing technologies remains a major challenge. Many such variants occur in tumor genes that have well...

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發表在:Mol Oncol
Main Authors: Dienstmann, Rodrigo, Dong, Fei, Borger, Darrell, Dias-Santagata, Dora, Ellisen, Leif W., Le, Long P., Iafrate, A. John
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2014
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528527/
https://ncbi.nlm.nih.gov/pubmed/24768039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.03.021
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