Secretome and degradome profiling shows that Kallikrein‐related peptidases 4, 5, 6, and 7 induce TGFβ‐1 signaling in ovarian cancer cells

Kallikrein‐related peptidases, in particular KLK4, 5, 6 and 7 (4–7), often have elevated expression levels in ovarian cancer. In OV‐MZ‐6 ovarian cancer cells, combined expression of KLK4–7 reduces cell adhesion and increases cell invasion and resistance to paclitaxel. The present work investigates h...

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Detaylı Bibliyografya
Yayımlandı:Mol Oncol
Asıl Yazarlar: Shahinian, Hasmik, Loessner, Daniela, Biniossek, Martin L., Kizhakkedathu, Jayachandran N., Clements, Judith A., Magdolen, Viktor, Schilling, Oliver
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2013
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528505/
https://ncbi.nlm.nih.gov/pubmed/24120346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.09.003
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