Suppression of the growth of human colorectal cancer cells by therapeutic stem cells expressing cytosine deaminase and interferon‐β via their tumor‐tropic effect in cellular and xenograft mouse models

Genetically engineered stem cells (GESTECs) exhibit a potent therapeutic efficacy via their strong tumor tropism toward cancer cells. In this study, we introduced the human parental neural stem cells, HB1.F3, with the human interferon beta (IFN‐β) gene which is a typical cytokine gene that has an an...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Yi, Bo-Rim, Park, Min-Ah, Lee, Hye-Rim, Kang, Nam-Hee, Choi, Kelvin J., Kim, Seung U., Choi, Kyung-Chul
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528496/
https://ncbi.nlm.nih.gov/pubmed/23403306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.01.004
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