Leptin increases HER2 protein levels through a STAT3‐mediated up‐regulation of Hsp90 in breast cancer cells

Obesity condition confers risks to breast cancer development and progression, and several reports indicate that the adipokine leptin, whose synthesis and plasma levels increase with obesity, might play an important role in modulating breast cancer cell phenotype. Functional crosstalk occurring betwe...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Giordano, Cinzia, Vizza, Donatella, Panza, Salvatore, Barone, Ines, Bonofiglio, Daniela, Lanzino, Marilena, Sisci, Diego, De Amicis, Francesca, Fuqua, Suzanne A.W., Catalano, Stefania, Andò, Sebastiano
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528468/
https://ncbi.nlm.nih.gov/pubmed/23228483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.11.002
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