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The metastasis‐associated molecule C4.4A promotes tissue invasion and anchorage independence by associating with the alpha6beta4 integrin

C4.4A is a metastasis‐associated molecule that functions appear to rely on associated alph6beta4 integrin. To corroborate the impact of the C4.4A‐alpha6beta4 integrin association on metastasis formation, C4.4A was knocked‐down in a highly metastatic rat pancreatic adenocarcinoma (ASML, ASML‐C4.4Akd)...

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Publicat a:Mol Oncol
Autors principals: Thuma, Florian, Ngora, Honoré, Zöller, Margot
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528461/
https://ncbi.nlm.nih.gov/pubmed/23727360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.05.002
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