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Nelfinavir and bortezomib inhibit mTOR activity via ATF4‐mediated sestrin‐2 regulation
Endoplasmic reticulum (ER) stress and autophagy are two basic cell survival mechanisms often occurring in concert. Extensive ER stress in cancer cells deliberately induced by chemotherapeutic drugs may lead to growth arrest and cell death. However, the link between ER stress and autophagy is not wel...
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| Publicado no: | Mol Oncol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528439/ https://ncbi.nlm.nih.gov/pubmed/23916134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.07.010 |
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