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Blocking the attachment of cancer cells in vivo with DNA aptamers displaying anti‐adhesive properties against the carcinoembryonic antigen

The formation of metastatic foci occurs through a series of cellular events, initiated by the attachment and aggregation of cancer cells leading to the establishment of micrometastases. We report the derivation of synthetic DNA aptamers bearing anti‐adhesive properties directed at cancer cells expre...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Orava, Erik W., Abdul-Wahid, Aws, Huang, Eric H.-B., Mallick, Amirul Islam, Gariépy, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528425/
https://ncbi.nlm.nih.gov/pubmed/23656757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.03.005
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