Meiotic recombination between yeast artificial chromosomes yields a single clone containing the entire BCL2 protooncogene.

The common translocation found in human follicular lymphoma, t(14;18)(q32;q21), results in deregulation of the BCL2 protoonocogene. The isolation of the intact gene would provide an essential substrate to analyze the molecular basis of this malignancy. Pulsed-field gel electrophoresis suggested that...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Silverman, G A, Green, E D, Young, R L, Jockel, J I, Domer, P H, Korsmeyer, S J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55284/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2263642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9913
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