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Cloning of the HLA class II region in yeast artificial chromosomes.

Yeast artificial chromosomes (YACs) have been applied to clone the entire class II region of the human major histocompatibility complex (MHC), including its flanking regions, in a contig over 1.5 million base pairs (bp) long. The human DNA inserts in the YACs have a size between 60 and 1300 kbp and...

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Detalhes bibliográficos
Main Authors: Ragoussis, J, Monaco, A, Mockridge, I, Kendall, E, Campbell, R D, Trowsdale, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51531/
https://ncbi.nlm.nih.gov/pubmed/1673791
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