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Lack of independent prognostic and predictive value of centromere 17 copy number changes in breast cancer patients with known HER2 and TOP2A status

The clinical benefit of anthracyclines has been connected to HER2 status, TOP2A status and centromere 17 copy numbers (CEN‐17). Data from a clinical trial randomizing patients to anthracyclines was used to assess whether the number of CEN‐17 in breast cancers may predict incremental responsiveness t...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Nielsen, Kirsten Vang, Ejlertsen, Bent, Møller, Susanne, Jensen, Maj-Britt, Balslev, Eva, Müller, Sven, Knoop, Ann, Mouridsen, Henning T.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528381/
https://ncbi.nlm.nih.gov/pubmed/22153616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.11.006
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