Lack of independent prognostic and predictive value of centromere 17 copy number changes in breast cancer patients with known HER2 and TOP2A status

The clinical benefit of anthracyclines has been connected to HER2 status, TOP2A status and centromere 17 copy numbers (CEN‐17). Data from a clinical trial randomizing patients to anthracyclines was used to assess whether the number of CEN‐17 in breast cancers may predict incremental responsiveness t...

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Опубликовано в: :Mol Oncol
Главные авторы: Nielsen, Kirsten Vang, Ejlertsen, Bent, Møller, Susanne, Jensen, Maj-Britt, Balslev, Eva, Müller, Sven, Knoop, Ann, Mouridsen, Henning T.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2011
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Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528381/
https://ncbi.nlm.nih.gov/pubmed/22153616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.11.006
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