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Drug development to overcome resistance to EGFR inhibitors in lung and colorectal cancer

Epidermal growth factor receptor (EGFR) is a validated target in different human malignancies. EGFR tyrosine kinase inhibitors (TKIs) are known to contribute considerably to the extension of progression‐free survival in EGFR‐mutant non‐small cell lung cancer and monoclonal antibodies (mAbs) targetin...

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書目詳細資料
發表在:Mol Oncol
Main Authors: Dienstmann, Rodrigo, De Dosso, Sara, Felip, Enriqueta, Tabernero, Josep
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528378/
https://ncbi.nlm.nih.gov/pubmed/22189054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.11.009
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