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The interaction of PKN3 with RhoC promotes malignant growth

PKN3 is an AGC‐family protein kinase implicated in growth of metastatic prostate cancer cells with phosphoinositide 3‐kinase pathway deregulation. The molecular mechanism, however, by which PKN3 contributes to malignant growth and tumorigenesis is not well understood. Using orthotopic mouse tumor mo...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Unsal-Kacmaz, Keziban, Ragunathan, Shoba, Rosfjord, Edward, Dann, Stephen, Upeslacis, Erik, Grillo, Mary, Hernandez, Richard, Mack, Fiona, Klippel, Anke
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528337/
https://ncbi.nlm.nih.gov/pubmed/22217540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.12.001
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