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Structural and genic characterization of stable genomic regions in breast cancer: Relevance to chemotherapy

BACKGROUND: Cancer genomes accumulate frequent and diverse chromosomal abnormalities as well as gene mutations but must maintain the ability to survive in vivo. We hypothesize that genetic selection acts to maintain tumour survival by preserving copy number of specific genes and genomic regions. Gen...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Park, Nicole I., Rogan, Peter K., Tarnowski, Heather E., Knoll, Joan H.M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528331/
https://ncbi.nlm.nih.gov/pubmed/22342187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.01.001
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