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Context-based FISH localization of genomic rearrangements within chromosome 15q11.2q13 duplicons

BACKGROUND: Segmental duplicons (SDs) predispose to an increased frequency of chromosomal rearrangements. These rearrangements can cause a diverse range of phenotypes due to haploinsufficiency, in cis positional effects or gene interruption. Genomic microarray analysis has revealed gene dosage chang...

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Detaylı Bibliyografya
Asıl Yazarlar: Khan, Wahab A, Knoll, Joan HM, Rogan, Peter K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171312/
https://ncbi.nlm.nih.gov/pubmed/21824424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-4-15
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