Focal adhesion kinase inhibitors are potent anti‐angiogenic agents

Focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase and scaffold protein localized to focal adhesions, is uniquely positioned at the convergence point of integrin and receptor tyrosine kinase signal transduction pathways. FAK is overexpressed in many tumor cells, hence various inhibitors targ...

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發表在:Mol Oncol
Main Authors: Cabrita, Miguel A., Jones, Laura M., Quizi, Jennifer L., Sabourin, Luc A., McKay, Bruce C., Addison, Christina L.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2011
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Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528320/
https://ncbi.nlm.nih.gov/pubmed/22075057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.10.004
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