Focal adhesion kinase inhibitors are potent anti‐angiogenic agents

Focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase and scaffold protein localized to focal adhesions, is uniquely positioned at the convergence point of integrin and receptor tyrosine kinase signal transduction pathways. FAK is overexpressed in many tumor cells, hence various inhibitors targ...

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Bibliografiska uppgifter
I publikationen:Mol Oncol
Huvudupphovsmän: Cabrita, Miguel A., Jones, Laura M., Quizi, Jennifer L., Sabourin, Luc A., McKay, Bruce C., Addison, Christina L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2011
Ämnen:
Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528320/
https://ncbi.nlm.nih.gov/pubmed/22075057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.10.004
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