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Focal adhesion kinase inhibitors are potent anti‐angiogenic agents
Focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase and scaffold protein localized to focal adhesions, is uniquely positioned at the convergence point of integrin and receptor tyrosine kinase signal transduction pathways. FAK is overexpressed in many tumor cells, hence various inhibitors targ...
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出版年: | Mol Oncol |
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主要な著者: | , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
John Wiley and Sons Inc.
2011
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528320/ https://ncbi.nlm.nih.gov/pubmed/22075057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.10.004 |
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