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Focal adhesion kinase inhibitors are potent anti‐angiogenic agents

Focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase and scaffold protein localized to focal adhesions, is uniquely positioned at the convergence point of integrin and receptor tyrosine kinase signal transduction pathways. FAK is overexpressed in many tumor cells, hence various inhibitors targ...

詳細記述

保存先:
書誌詳細
出版年:Mol Oncol
主要な著者: Cabrita, Miguel A., Jones, Laura M., Quizi, Jennifer L., Sabourin, Luc A., McKay, Bruce C., Addison, Christina L.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528320/
https://ncbi.nlm.nih.gov/pubmed/22075057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.10.004
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