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Focal adhesion kinase inhibitors are potent anti‐angiogenic agents

Focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase and scaffold protein localized to focal adhesions, is uniquely positioned at the convergence point of integrin and receptor tyrosine kinase signal transduction pathways. FAK is overexpressed in many tumor cells, hence various inhibitors targ...

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Foilsithe in:Mol Oncol
Main Authors: Cabrita, Miguel A., Jones, Laura M., Quizi, Jennifer L., Sabourin, Luc A., McKay, Bruce C., Addison, Christina L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528320/
https://ncbi.nlm.nih.gov/pubmed/22075057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.10.004
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