Multiregion ultra‐deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer

Intratumor heterogeneity (ITH) contributes to cancer progression and chemoresistance. We sought to comprehensively describe ITH of somatic mutations, copy number, and transcriptomic alterations involving clinically and biologically relevant gene pathways in colorectal cancer (CRC). We performed mult...

全面介紹

Na minha lista:
書目詳細資料
發表在:Mol Oncol
Main Authors: Suzuki, Yuka, Ng, Sarah Boonhsi, Chua, Clarinda, Leow, Wei Qiang, Chng, Jermain, Liu, Shi Yang, Ramnarayanan, Kalpana, Gan, Anna, Ho, Dan Liang, Ten, Rachel, Su, Yan, Lezhava, Alexandar, Lai, Jiunn Herng, Koh, Dennis, Lim, Kiat Hon, Tan, Patrick, Rozen, Steven G., Tan, Iain Beehuat
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527459/
https://ncbi.nlm.nih.gov/pubmed/28145097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12012
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍