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Genomic analysis of chimeric human cytomegalovirus vaccine candidates derived from strains Towne and Toledo

Human cytomegalovirus (HCMV) is an important opportunistic pathogen in immunocompromised patients and a major cause of congenital birth defects when acquired in utero. In the 1990s, four chimeric viruses were constructed by replacing genome segments of the high passage Towne strain with segments of...

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Publicado en:Virus Genes
Autores principales: Suárez, Nicolás M., Lau, Betty, Kemble, George M., Lee, Ronzo, Mocarski, Edward S., Wilkinson, Gavin W. G., Adler, Stuart P., McVoy, Michael A., Davison, Andrew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527331/
https://ncbi.nlm.nih.gov/pubmed/28391502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11262-017-1452-0
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