Genomic analysis of chimeric human cytomegalovirus vaccine candidates derived from strains Towne and Toledo

Human cytomegalovirus (HCMV) is an important opportunistic pathogen in immunocompromised patients and a major cause of congenital birth defects when acquired in utero. In the 1990s, four chimeric viruses were constructed by replacing genome segments of the high passage Towne strain with segments of...

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Bibliografiske detaljer
Udgivet i:Virus Genes
Main Authors: Suárez, Nicolás M., Lau, Betty, Kemble, George M., Lee, Ronzo, Mocarski, Edward S., Wilkinson, Gavin W. G., Adler, Stuart P., McVoy, Michael A., Davison, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527331/
https://ncbi.nlm.nih.gov/pubmed/28391502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11262-017-1452-0
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