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Genomic analysis of chimeric human cytomegalovirus vaccine candidates derived from strains Towne and Toledo

Human cytomegalovirus (HCMV) is an important opportunistic pathogen in immunocompromised patients and a major cause of congenital birth defects when acquired in utero. In the 1990s, four chimeric viruses were constructed by replacing genome segments of the high passage Towne strain with segments of...

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Vydáno v:Virus Genes
Hlavní autoři: Suárez, Nicolás M., Lau, Betty, Kemble, George M., Lee, Ronzo, Mocarski, Edward S., Wilkinson, Gavin W. G., Adler, Stuart P., McVoy, Michael A., Davison, Andrew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527331/
https://ncbi.nlm.nih.gov/pubmed/28391502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11262-017-1452-0
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