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Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis

Knowledge about the region-specific absorption profiles from the gastrointestinal tract of orally administered drugs is a critical factor guiding dosage form selection in drug development. We have used a novel approach to study three well-characterized permeability and absorption marker drugs in the...

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Vydáno v:Sci Rep
Hlavní autoři: Nilsson, Anna, Peric, Alexandra, Strimfors, Marie, Goodwin, Richard J. A., Hayes, Martin A., Andrén, Per E., Hilgendorf, Constanze
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526999/
https://ncbi.nlm.nih.gov/pubmed/28743866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06583-4
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