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Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis
Knowledge about the region-specific absorption profiles from the gastrointestinal tract of orally administered drugs is a critical factor guiding dosage form selection in drug development. We have used a novel approach to study three well-characterized permeability and absorption marker drugs in the...
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Vydáno v: | Sci Rep |
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Hlavní autoři: | , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Nature Publishing Group UK
2017
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526999/ https://ncbi.nlm.nih.gov/pubmed/28743866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06583-4 |
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