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Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism
Dihydroneopterin triphosphate pyrophosphatase (DHNTPase), a member of the Mg(2+) dependent Nudix hydrolase superfamily, is the recently-discovered enzyme that functions in the second step of the pterin branch of the folate biosynthetic pathway in E. coli. DHNTPase is of interest because inhibition o...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526541/ https://ncbi.nlm.nih.gov/pubmed/28742822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180241 |
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