The MalR type regulator AcrC is a transcriptional repressor of acarbose biosynthetic genes in Actinoplanes sp. SE50/110

BACKGROUND: Acarbose is used in the treatment of diabetes mellitus type II and is produced by Actinoplanes sp. SE50/110. Although the biosynthesis of acarbose has been intensively studied, profound knowledge about transcription factors involved in acarbose biosynthesis and their binding sites has be...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Genomics
Prif Awduron: Wolf, Timo, Droste, Julian, Gren, Tetiana, Ortseifen, Vera, Schneiker-Bekel, Susanne, Zemke, Till, Pühler, Alfred, Kalinowski, Jörn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526262/
https://ncbi.nlm.nih.gov/pubmed/28743243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3941-x
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