CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease activity

BACKGROUND: Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation. In the current study, we aimed to investigate the possible pathogenic implication of autophagy in T lymphocytes in...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Alessandri, Cristiano, Ciccia, Francesco, Priori, Roberta, Astorri, Elisa, Guggino, Giuliana, Alessandro, Riccardo, Rizzo, Aroldo, Conti, Fabrizio, Minniti, Antonina, Barbati, Cristiana, Vomero, Marta, Pendolino, Monica, Finucci, Annacarla, Ortona, Elena, Colasanti, Tania, Pierdominici, Marina, Malorni, Walter, Triolo, Giovanni, Valesini, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526255/
https://ncbi.nlm.nih.gov/pubmed/28743286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1385-y
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