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Inhibition of T cell-mediated inflammation in uveitis by a novel anti-CD3 antibody

BACKGROUND: A novel anti-mouse CD3ε antibody, Dow2, recognizes mouse CD3ε without activating T cells and suppresses T-cell activation. The purpose of this study was to determine whether Dow2 can inhibit T cells in uveitis. METHODS: Experimental autoimmune uveitis (EAU) was induced in mice by immuniz...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arthritis Res Ther
Prif Awduron: Sugita, Sunao, Shimizu, Jun, Makabe, Kenichi, Keino, Hiroshi, Watanabe, Takeshi, Takahashi, Masayo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526238/
https://ncbi.nlm.nih.gov/pubmed/28743289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1379-9
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