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Inhibition of T cell-mediated inflammation in uveitis by a novel anti-CD3 antibody
BACKGROUND: A novel anti-mouse CD3ε antibody, Dow2, recognizes mouse CD3ε without activating T cells and suppresses T-cell activation. The purpose of this study was to determine whether Dow2 can inhibit T cells in uveitis. METHODS: Experimental autoimmune uveitis (EAU) was induced in mice by immuniz...
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| Publicado no: | Arthritis Res Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526238/ https://ncbi.nlm.nih.gov/pubmed/28743289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1379-9 |
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