Evaluation of the C-domain of heparanase during AGE-induced macrophage inflammatory response

Diabetic vasculopathy is intensified by macrophage inflammation caused by advanced glycation end products (AGEs). Heparanase (HPA) is a unique endoglycosidase, which cleaves heparan sulfate proteoglycans (HSPGs) including syndecan-1 (Syn-1) to further stimulate macrophage cell migration and inflamma...

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Pubblicato in:Exp Ther Med
Autori principali: Qin, Qiaojing, Xu, Guang, Qi, Weiwei, Guo, Mei, Wang, Zhaoxia, Xu, Wangjie, Qiao, Zhongdong, Gu, Yong, Niu, Jianying
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526102/
https://ncbi.nlm.nih.gov/pubmed/28810553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4609
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