Tissue kallikrein protects against ischemic stroke by suppressing TLR4/NF-κB and activating Nrf2 signaling pathway in rats

Brain damage following cerebral ischemia-reperfusion (I/R) is a complicated pathophysiological course, in which inflammation and oxidative stress have been suggested to serve an important role. Toll-like receptor 4 (TLR4) has been suggested to be involved in secondary inflammatory process in cerebra...

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Pubblicato in:Exp Ther Med
Autori principali: Yang, Jiawei, Su, Jianhua, Wan, Fen, Yang, Nan, Jiang, Haibo, Fang, Mingming, Xiao, Hang, Wang, Jun, Tang, Jinrong
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525899/
https://ncbi.nlm.nih.gov/pubmed/28810574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4614
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