Conditionally Immortal Slc4a11(−/−) Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11(−/−) Mouse Model

PURPOSE: To establish conditionally immortal mouse corneal endothelial cell lines with genetically matched Slc4a11(+/+) and Slc4a11(−/−) mice as a model for investigating pathology and therapies for SLC4A11 associated congenital hereditary endothelial dystrophy (CHED) and Fuchs' endothelial cor...

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Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Zhang, Wenlin, Ogando, Diego G., Kim, Edward T., Choi, Moon-Jung, Li, Hongde, Tenessen, Jason M., Bonanno, Joseph A.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2017
Subjects:
Cornea
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525555/
https://ncbi.nlm.nih.gov/pubmed/28738416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-21781
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