Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium

Corneal endothelium (CE) is among the most metabolically active tissues in the body. This elevated metabolic rate helps the CE maintain corneal transparency by its ion and fluid transport properties, which when disrupted, leads to visual impairment. Here we demonstrate that glutamine catabolism (glu...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Zhang, Wenlin, Li, Hongde, Ogando, Diego G., Li, Shimin, Feng, Matthew, Price, Francis W., Tennessen, Jason M., Bonanno, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474426/
https://ncbi.nlm.nih.gov/pubmed/28117276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.01.004
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