Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium

Corneal endothelium (CE) is among the most metabolically active tissues in the body. This elevated metabolic rate helps the CE maintain corneal transparency by its ion and fluid transport properties, which when disrupted, leads to visual impairment. Here we demonstrate that glutamine catabolism (glu...

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Publicat a:EBioMedicine
Autors principals: Zhang, Wenlin, Li, Hongde, Ogando, Diego G., Li, Shimin, Feng, Matthew, Price, Francis W., Tennessen, Jason M., Bonanno, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474426/
https://ncbi.nlm.nih.gov/pubmed/28117276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.01.004
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