Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium

Corneal endothelium (CE) is among the most metabolically active tissues in the body. This elevated metabolic rate helps the CE maintain corneal transparency by its ion and fluid transport properties, which when disrupted, leads to visual impairment. Here we demonstrate that glutamine catabolism (glu...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Zhang, Wenlin, Li, Hongde, Ogando, Diego G., Li, Shimin, Feng, Matthew, Price, Francis W., Tennessen, Jason M., Bonanno, Joseph A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474426/
https://ncbi.nlm.nih.gov/pubmed/28117276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.01.004
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