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Structure–activity studies of non-steroid analogues structurally-related to neuroprotective estrogens()

Estrone and 17β-estradiol are phenolic steroids that are known to be neuroprotective in multiple models of neuronal injury. Previous studies have identified the importance of their phenolic steroid A-ring for neuroprotection and have identified ortho substituents at the C-2 and C-4 positions on the...

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Dettagli Bibliografici
Pubblicato in:Org Biomol Chem
Autori principali: Qian, Mingxing, Engler-Chiurazzi, Elizabeth B., Lewis, Sara E., Rath, Nigam P., Simpkins, James W., Covey, Douglas F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525543/
https://ncbi.nlm.nih.gov/pubmed/27714297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob01726f
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