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A Novel Mechanism of Non-feminizing Estrogens in Neuroprotection

Estrogens are potent and efficacious neuroprotectants both in vitro and in vivo in a variety of models of neurotoxicity. We determined the structural requirements for neuroprotection in an in vitro assay using a panel of more than 70 novel estratrienes, synthesized to reduce or eliminate estrogen re...

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Publicado en:Exp Gerontol
Main Authors: Engler-Chiurazzi, Elizabeth B., Covey, Douglas F., Simpkins, James W.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415429/
https://ncbi.nlm.nih.gov/pubmed/27818250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2016.10.013
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