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Immunization with Recombinant TcdB-Encapsulated Nanocomplex Induces Protection against Clostridium difficile Challenge in a Mouse Model

Clostridium difficile is considered to be one of the major cause of infectious diarrhea in healthcare systems worldwide. Symptoms of C. difficile infection are caused largely by the production of two cytotoxins: toxin A (TcdA) and toxin B (TcdB). Vaccine development is considered desirable as it wou...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Liu, Yi-Wen, Chen, Yu-Hung, Chen, Jenn-Wei, Tsai, Pei-Jane, Huang, I-Hsiu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525027/
https://ncbi.nlm.nih.gov/pubmed/28790999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01411
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