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Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF

Phenazines are bacterial virulence and survival factors with important roles in infectious disease. PhzF catalyzes a key reaction in their biosynthesis by isomerizing (2 S,3 S)-2,3-dihydro-3-hydroxy anthranilate (DHHA) in two steps, a [1,5]-hydrogen shift followed by tautomerization to an aminoketon...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Diederich, Christina, Leypold, Mario, Culka, Martin, Weber, Hansjörg, Breinbauer, Rolf, Ullmann, G. Matthias, Blankenfeldt, Wulf
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524880/
https://ncbi.nlm.nih.gov/pubmed/28740244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06278-w
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