Mechanisms of Smooth Muscle Cell Differentiation Are Distinctly Altered in Thoracic Aortic Aneurysms Associated with Bicuspid or Tricuspid Aortic Valves

Cellular and molecular mechanisms of thoracic aortic aneurysm are not clear and therapeutic approaches are mostly absent. Thoracic aortic aneurysm is associated with defective differentiation of smooth muscle cells (SMC) of aortic wall. Bicuspid aortic valve (BAV) comparing to tricuspid aortic valve...

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Publicat a:Front Physiol
Autors principals: Ignatieva, Elena, Kostina, Daria, Irtyuga, Olga, Uspensky, Vladimir, Golovkin, Alexey, Gavriliuk, Natalia, Moiseeva, Olga, Kostareva, Anna, Malashicheva, Anna
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524772/
https://ncbi.nlm.nih.gov/pubmed/28790933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00536
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