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Mechanisms of Smooth Muscle Cell Differentiation Are Distinctly Altered in Thoracic Aortic Aneurysms Associated with Bicuspid or Tricuspid Aortic Valves

Cellular and molecular mechanisms of thoracic aortic aneurysm are not clear and therapeutic approaches are mostly absent. Thoracic aortic aneurysm is associated with defective differentiation of smooth muscle cells (SMC) of aortic wall. Bicuspid aortic valve (BAV) comparing to tricuspid aortic valve...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Ignatieva, Elena, Kostina, Daria, Irtyuga, Olga, Uspensky, Vladimir, Golovkin, Alexey, Gavriliuk, Natalia, Moiseeva, Olga, Kostareva, Anna, Malashicheva, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524772/
https://ncbi.nlm.nih.gov/pubmed/28790933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00536
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