TGF-β1 Downregulates the Expression of CX(3)CR1 by Inducing miR-27a-5p in Primary Human NK Cells

Activity of human natural killer (NK) cells against cancer cells is deeply suppressed by TGF-β1, an immunomodulatory cytokine that is released and activated in the tumor microenvironment. Moreover, our previous data showed that TGF-β1 modifies the chemokine receptor repertoire of NK cells. In partic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Regis, Stefano, Caliendo, Fabio, Dondero, Alessandra, Casu, Beatrice, Romano, Filomena, Loiacono, Fabrizio, Moretta, Alessandro, Bottino, Cristina, Castriconi, Roberta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524732/
https://ncbi.nlm.nih.gov/pubmed/28791023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00868
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados