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Novel Molecule Exhibiting Selective Affinity for GABA(A) Receptor Subtypes
Aminoquinoline derivatives were evaluated against a panel of receptors/channels/transporters in radioligand binding experiments. One of these derivatives (DCUK-OEt) displayed micromolar affinity for brain γ-aminobutyric acid type A (GABA(A)) receptors. DCUK-OEt was shown to be a positive allosteric...
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| 發表在: | Sci Rep |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5524711/ https://ncbi.nlm.nih.gov/pubmed/28740086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05966-x |
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