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Epidermal Growth Factor Receptor (EGFR) Mutations in Small Cell Lung Cancers: Two Cases and a Review of the Literature

Activating mutations in the epidermal growth factor receptor (EGFR) gene are exceedingly rare in small cell lung cancer (SCLC). We present two cases of SCLC harboring EGFR mutations, one in an 82 year-old male smoker with a combined SCLC and adenocarcinoma with a novel D855H point mutation in exon 2...

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Détails bibliographiques
Publié dans:Lung Cancer
Auteurs principaux: Siegele, Bradford J., Shilo, Konstantin, Chao, Bo H., Carbone, David, Zhao, Weiqiang, Ioffe, Olga, Franklin, Wilbur A., Edelman, Martin J., Aisner, Dara L.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524560/
https://ncbi.nlm.nih.gov/pubmed/27040854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2016.02.012
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