Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)

Non-small cell lung cancer (NSCLC) has limited treatment options. Expression of the RNA-binding protein (RBP) Musashi-2 (MSI2) is elevated in a subset of non-small cell lung cancer (NSCLC) tumors upon progression, and drives NSCLC metastasis. We evaluated the mechanism of MSI2 action in NSCLC to gai...

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發表在:Oncogenesis
Main Authors: Makhov, Petr, Bychkov, Igor, Faezov, Bulat, Deneka, Alexander, Kudinov, Alexander, Nicolas, Emmanuelle, Brebion, Rohan, Avril, Eleanor, Cai, Kathy Q., Kharin, Leonid V., Voloshin, Mark, Frantsiyants, Elena, Karnaukhov, Nikolay, Kit, Oleg I., Topchu, Iuliia, Fazliyeva, Rushaniya, Nikonova, Anna S., Serebriiskii, Ilya G., Borghaei, Hossein, Edelman, Martin, Dulaimi, Essel, Golemis, Erica A., Boumber, Yanis
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961039/
https://ncbi.nlm.nih.gov/pubmed/33723247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-021-00317-y
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