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ImmunoPET imaging of murine CD4(+) T cells using anti-CD4 cys-diabody: Effects of protein dose on T cell function and imaging

PURPOSE: Molecular imaging of CD4(+) T cells throughout the body has implications for monitoring autoimmune disease and immunotherapy of cancer. Given the key role of these cells in regulating immunity, it is important to develop a biologically inert probe. GK1.5 cys-diabody (cDb), a previously deve...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Freise, Amanda C, Zettlitz, Kirstin A, Salazar, Felix B, Lu, Xiang, Tavaré, Richard, Wu, Anna M
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524218/
https://ncbi.nlm.nih.gov/pubmed/27966069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-016-1032-z
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